It looks like you're using Internet Explorer 11 or older. This website works best with modern browsers such as the latest versions of Chrome, Firefox, Safari, and Edge. If you continue with this browser, you may see unexpected results.
UpToDate® is an evidence-based, physician-authored clinical decision support resource which clinicians trust to make the right point-of-care decisions.
Login with your UpToDate username and password. First Time Users must register before logging in. See the UpToDate Guide for more information.
Comprehensive citation and abstract database, including references from the life sciences, health sciences, physical sciences, and social sciences & humanities
Full text of Harrison's Principles of Internal Medicine, 20th Edition. Includes illustrations as well as expanded features such as additional references, links to MEDLINE abstracts, and unique online content. Updated daily.